- 1 Vitamin B 12
- 2 damage increased vitamin B 12
- 3 Warning use of vitamin B 12
- 4 Drug interactions with vitamin B-12
- 5 The recommended amounts of vitamin B 12
- 6 References
Vitamin B-12, or the so-called Eopalaman (in English: Cobalamin) is one of the B vitamins dissolved in the water, ie, they can go through the blood stream to the various parts of the body, as it is the largest vitamin and The more complex structure than the rest of vitamins, and is important for the health of the tissue nerve and brain function, and in addition to that it has a role in the production of red blood cells, it is worth mentioning that the body can keep this vitamin for up to 4 years, the decrease in levels occurs when not eating sufficient amounts of sources; As it is available in meat are naturally not normally found in plant sources, so people may suffer who do not eat meat shortage, and may need to eat food Mkmlath to compensate for this deficiency. 
Damage to increase vitamin B 12
Eating large amounts of vitamin B 12 does not cause any poisoning or damage side, it was found that eating Mlegramen a day of this vitamin for a month, or taking muscle from him an injection at a dose milligram one month did not cause any damage, it may be because the body does not absorb only the amount of small of this vitamin when taken by mouth, but it did not specify the US food and nutrition maximum amounts allowed of vitamin b 12,  but eating can cause some side effects, including: 
- Restenosis (in English: Restenosis) after undergoing surgery in the cultivation of a network of blood vessels.
- Low levels of potassium.
- Itchy skin and its burning.
- Increase blood volume and the number of red blood cells.
- Difficulty swallowing.
- The color of urine change.
- Acute gout (episodes in English: Gout flare-up).
- Skin rash.
The injection of vitamin B-12 may cause some damage as well, including: 
- Light damage: It is recommended to consult a doctor if these continued damage problems, namely: Pain, redness, and itching at the injection site. Diarrhea light. Feeling swollen body.
- Pain, redness, and itching at the injection site.
- Diarrhea light.
- Feeling swollen body.
- Medium damage: must suffer from these problems, consult your doctor quickly and immediately, namely: Muscle pain. Arrhythmia. Fatigue and weakness is unjustified. Swelling of the feet and knees.
- Muscle pain.
- Fatigue and weakness is unjustified.
- Swelling of the feet and knees.
- Severe damage: and when they occur must obtain emergency medical assistance, and such damage: Swelling of the face, throat, tongue, and itching in them. Breathing difficulty. Severe dizziness. Sudden change in the consideration. Stammering to speak.
- Swelling of the face, throat, tongue, and itching in them.
- Breathing difficulty.
- Severe dizziness.
- Sudden change in the consideration.
- Stammering to speak.
Warning the use of vitamin B 12
There are some people who warn of taking vitamin B12 and recall of these people: 
- Pregnant women and breastfeeding: The intake of vitamin B 12, the recommended amount for pregnant and breastfeeding women is safe, but does not know if eating larger amounts of it is safe during pregnancy and lactation, so it is advisable to avoid eating larger quantities than recommended amounts.
- Sensitivity direction cobalt or cobalamin: should the people who are suffering from this case, avoid the use of vitamin B 12.
- People with impairment of Leber hereditary optic nerve: the eating causes people with this disease to vitamin B 12 serious damage to the nerve in the eye, which can lead to blindness, so people with this disease are advised to avoid vitamin B12.
- People with anemia megaloblastic anemia: (English: Megaloblastic anemia); A condition that is sometimes treated with vitamin B-12, but it may cause serious collateral damage, so you should not take this vitamin to treat this condition only under the supervision of a doctor.
- People who suffer from high numbers of red blood cells: a condition called the large number of real reds (in English: Polycythemia vera), and may cause treatment with vitamin B-12 appearance of the disease symptoms.
Drug interactions with vitamin B-12
Can vitamin B-12 that interferes with many medicines, as there are some medicines that affect levels in the body, so people are advised those taking these drugs to consult a doctor about the levels of vitamin B-12 have, and recall of these drugs: 
- Chloramphenicol (in English: Chloramphenicol): It is an antibiotic for bacteria, has few studies have indicated that it could interfere with the response of red blood cells with vitamin B12 supplements.
- Drugs proton pump inhibitors: (English: Proton pump inhibitors); Which is used to treat stomach ulcers, diabetes recoil gastric reflux (in English: Gastroesophageal reflux disease), such as Allansoprasul, and omeprazole, it has found that these drugs can interfere with the absorption of vitamin B12 from food through slowing down the secretion of hydrochloric acid in the stomach, but it is still not Certain.
- Blockers future Histamine 2: (English: H2 antagonist); Which is used to treat stomach ulcers, it has found that these drugs can cause vitamin B12 deficiency, because they interfere with the absorption of foods, but there is not enough evidence to confirm that.
- Almitvuorman: a drug that lowers glucose levels in the blood, and is used to treat patients with diabetes, and may cause a change in bowel movement, or increasing the growth of bacteria which, as it may alter the reception of cells in another part of the small intestine internal factor (in English: Intrinsic factor ) which carries the vitamin b-12, which reduces the absorption, some studies have indicated that it can give calcium supplements improve the absorption of vitamin b-12 problems caused by eating metformin.
The recommended amounts of vitamin B 12
The following table shows the allowable quantities and recommended (in English: Recommended Dietary Allowances) of vitamin B-12, according to the Food and Nutrition Council recommends (in English: Food and Nutrition Board): 
- ↑ Christian Nordqvist (28-11-2017), "Everything you need to know about vitamin B-12"، www.medicalnewstoday.com, Retrieved 2-11-2018. Edited.
- ↑ "Vitamin B12", www.lpi.oregonstate.edu, Retrieved 2-11-2018. Edited.
- ↑ Emily Cronkleton (26-5-2017), "Can Vitamin B-12 Cause Side Effects?"، www.healthline.com, Retrieved 2-11-2018. Edited.
- ↑ Jayne Leonard (4-7-2017), "Who needs vitamin B-12 shots and why?"، www.medicalnewstoday.com, Retrieved 2-11-2018. Edited.
- ↑ "VITAMIN B12", www.webmd.com, Retrieved 2-11-2018. Edited.
- ^ أ ب "Vitamin B12 Fact Sheet for Health Professionals", www.ods.od.nih.gov, Retrieved 2-11-2018. Edited.
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